The brain’s complexity is apparent from the incredible diversity in its cell types. To form the functional circuitry necessary to achieve sophisticated cognitive and motor functions, neural progenitors must make each type of neural cell at the right place and time and in the correct proportions.
All cells have the same genome, but each neural cell type expresses a specific subset of genes guided by a blueprint that was established within the progenitor. We are exploring the origins of neural diversity by studying how neural progenitor competence – the ability or potential to specify different cell types – is developmentally regulated by changes in nuclear architecture.
Tanguy Rene Vincent Lucas
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Slide 1: Minoree at her desk, holding a paper and looking at her laptop.
Slide 2: Group photo of lab members
Slide 3: Minoree pipetting a solution from small tube
Slide 4: Tanguy explaining something to the lab in front on a whiteboard
Slide 5: Natalia pipetting a solution
Slide 6: Minoree with fly popcage
Slide 7: Maggie with successful gel electrophoresis bands
Slide 8: Tanguy with fly vials on the microscope
Slide 9: Sofiya and Natalia discussing book
Slide 10: Sofiya fixing embryos
Slide 11: Gillie and Minoree next to computer display showing stained embryo
Slide 12: Gillie on microscope
Slide 13: Minoree, Gillie, and Richard looking at a computer display showing a stained embryo.